| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACOT13 | UBIAD1 | ENSAPLP00000027358 | ENSAPLP00000008059 | Acyl-CoA thioesterase 13. | UbiA prenyltransferase domain containing 1. | 0.827 |
| COQ2 | COQ5 | ENSAPLP00000011779 | ENSAPLP00000014977 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.887 |
| COQ2 | DHDDS | ENSAPLP00000011779 | ENSAPLP00000008568 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.661 |
| COQ2 | ENSAPLP00000030953 | ENSAPLP00000011779 | ENSAPLP00000030953 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.850 |
| COQ2 | GGCX | ENSAPLP00000011779 | ENSAPLP00000016985 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Gamma-glutamyl carboxylase. | 0.668 |
| COQ2 | HMGCR | ENSAPLP00000011779 | ENSAPLP00000005889 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.440 |
| COQ2 | NUS1 | ENSAPLP00000011779 | ENSAPLP00000015485 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.644 |
| COQ2 | UBIAD1 | ENSAPLP00000011779 | ENSAPLP00000008059 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | UbiA prenyltransferase domain containing 1. | 0.842 |
| COQ5 | COQ2 | ENSAPLP00000014977 | ENSAPLP00000011779 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.887 |
| COQ5 | HMGCR | ENSAPLP00000014977 | ENSAPLP00000005889 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.544 |
| COQ5 | UBIAD1 | ENSAPLP00000014977 | ENSAPLP00000008059 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | UbiA prenyltransferase domain containing 1. | 0.702 |
| DHDDS | COQ2 | ENSAPLP00000008568 | ENSAPLP00000011779 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.661 |
| DHDDS | ENSAPLP00000030953 | ENSAPLP00000008568 | ENSAPLP00000030953 | Alkyl transferase; Belongs to the UPP synthase family. | Nudix hydrolase domain-containing protein. | 0.742 |
| DHDDS | HMGCR | ENSAPLP00000008568 | ENSAPLP00000005889 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.458 |
| DHDDS | NUS1 | ENSAPLP00000008568 | ENSAPLP00000015485 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.999 |
| DHDDS | UBIAD1 | ENSAPLP00000008568 | ENSAPLP00000008059 | Alkyl transferase; Belongs to the UPP synthase family. | UbiA prenyltransferase domain containing 1. | 0.641 |
| DISP3 | FBXO2 | ENSAPLP00000008120 | ENSAPLP00000008489 | Dispatched RND transporter family member 3. | F-box protein 2. | 0.793 |
| DISP3 | UBIAD1 | ENSAPLP00000008120 | ENSAPLP00000008059 | Dispatched RND transporter family member 3. | UbiA prenyltransferase domain containing 1. | 0.746 |
| ENSAPLP00000030953 | COQ2 | ENSAPLP00000030953 | ENSAPLP00000011779 | Nudix hydrolase domain-containing protein. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.850 |
| ENSAPLP00000030953 | DHDDS | ENSAPLP00000030953 | ENSAPLP00000008568 | Nudix hydrolase domain-containing protein. | Alkyl transferase; Belongs to the UPP synthase family. | 0.742 |