| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C2orf69 | TRMT5 | ENSAPLP00000000333 | ENSAPLP00000023712 | Chromosome 2 open reading frame 69. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.400 |
| C2orf69 | TYW5 | ENSAPLP00000000333 | ENSAPLP00000008073 | Chromosome 2 open reading frame 69. | tRNA-yW synthesizing protein 5. | 0.669 |
| JMJD8 | RIOX2 | ENSAPLP00000016371 | ENSAPLP00000004239 | Jumonji domain containing 8. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | 0.665 |
| JMJD8 | TYW5 | ENSAPLP00000016371 | ENSAPLP00000008073 | Jumonji domain containing 8. | tRNA-yW synthesizing protein 5. | 0.646 |
| RIOX2 | JMJD8 | ENSAPLP00000004239 | ENSAPLP00000016371 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | Jumonji domain containing 8. | 0.665 |
| RIOX2 | RPL27A | ENSAPLP00000004239 | ENSAPLP00000003584 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. | 0.987 |
| RIOX2 | TYW5 | ENSAPLP00000004239 | ENSAPLP00000008073 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | tRNA-yW synthesizing protein 5. | 0.668 |
| RPL27A | RIOX2 | ENSAPLP00000003584 | ENSAPLP00000004239 | Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | 0.987 |
| RPL27A | TYW5 | ENSAPLP00000003584 | ENSAPLP00000008073 | Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. | tRNA-yW synthesizing protein 5. | 0.620 |
| SLC38A7 | TYW5 | ENSAPLP00000006662 | ENSAPLP00000008073 | Solute carrier family 38 member 7. | tRNA-yW synthesizing protein 5. | 0.612 |
| TRMT5 | C2orf69 | ENSAPLP00000023712 | ENSAPLP00000000333 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Chromosome 2 open reading frame 69. | 0.400 |
| TRMT5 | TYW3 | ENSAPLP00000023712 | ENSAPLP00000027887 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 3 homolog. | 0.755 |
| TRMT5 | TYW5 | ENSAPLP00000023712 | ENSAPLP00000008073 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 5. | 0.852 |
| TRMT5 | U3IWF3_ANAPP | ENSAPLP00000023712 | ENSAPLP00000011578 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Flavodoxin-like domain-containing protein. | 0.731 |
| TYW3 | TRMT5 | ENSAPLP00000027887 | ENSAPLP00000023712 | tRNA-yW synthesizing protein 3 homolog. | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.755 |
| TYW3 | TYW5 | ENSAPLP00000027887 | ENSAPLP00000008073 | tRNA-yW synthesizing protein 3 homolog. | tRNA-yW synthesizing protein 5. | 0.667 |
| TYW3 | U3IWF3_ANAPP | ENSAPLP00000027887 | ENSAPLP00000011578 | tRNA-yW synthesizing protein 3 homolog. | Flavodoxin-like domain-containing protein. | 0.904 |
| TYW5 | C2orf69 | ENSAPLP00000008073 | ENSAPLP00000000333 | tRNA-yW synthesizing protein 5. | Chromosome 2 open reading frame 69. | 0.669 |
| TYW5 | JMJD8 | ENSAPLP00000008073 | ENSAPLP00000016371 | tRNA-yW synthesizing protein 5. | Jumonji domain containing 8. | 0.646 |
| TYW5 | RIOX2 | ENSAPLP00000008073 | ENSAPLP00000004239 | tRNA-yW synthesizing protein 5. | Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. | 0.668 |