STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (847 aa)    
Predicted Functional Partners:
TMEM30A
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.830
ATP8A1-2
PhoLip_ATPase_N domain-containing protein.
 
      0.728
U3IS51_ANAPP
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
   
 0.632
CPLX1
Uncharacterized protein.
      
 0.609
ENSAPLP00000017712
Olfactory receptor.
      
 0.594
ZNF410
Zinc finger protein 410.
    
 0.550
SAXO2
Stabilizer of axonemal microtubules 2.
   
 
 0.474
U3IXJ3_ANAPP
Uncharacterized protein.
    
 
 0.459
PLN
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.444
U3I0X7_ANAPP
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
    
 0.400
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.