Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIPBLNipped-B protein. (2783 aa)    
Predicted Functional Partners:
MAU2
MAU2 sister chromatid cohesion factor.
    
 0.999
SMC3
Structural maintenance of chromosomes protein.
   
 0.997
SMC1B
Structural maintenance of chromosomes protein.
   
 0.977
PHF3
PHD finger protein 3.
   
  
 0.961
PDS5A
PDS5 cohesin associated factor A.
   
 0.958
PDS5B
PDS5 cohesin associated factor B.
   
 0.956
RAD21
RAD21 cohesin complex component.
   
 0.945
WAPL
WAPL cohesin release factor.
   
 0.940
RAD21L1
RAD21 cohesin complex component like 1.
   
 0.928
STAG2
Stromal antigen 2.
   
 0.900
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (16%) [HD]