Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBK1TANK binding kinase 1. (600 aa)    
Predicted Functional Partners:
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.996
STING1
Transmembrane protein 173.
   
 0.995
TANK
TRAF family member associated NFKB activator.
   
 0.992
OPTN
Optineurin.
   
 0.988
IRF7
Interferon regulatory factor 7.
    
 0.986
SQSTM1
Uncharacterized protein.
    
 0.984
CALCOCO2
Uncharacterized protein.
    
 0.981
DDX3X
Uncharacterized protein; Belongs to the DEAD box helicase family.
    
 0.961
MAVS
CARD_2 domain-containing protein.
    
 0.940
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.934
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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