Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MICU1Mitochondrial calcium uptake 1. (439 aa)    
Predicted Functional Partners:
MICU2
Mitochondrial calcium uptake 2.
    
0.998
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.998
MCU
Mitochondrial calcium uniporter.
    
 0.994
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.980
MICU3
Mitochondrial calcium uptake family member 3.
   
0.977
PHB2
Prohibitin.
    
 0.839
COX11
Cytochrome c oxidase copper chaperone COX11.
      
 0.769
PPP6R3
Protein phosphatase 6 regulatory subunit 3.
      
 0.750
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
     
 0.740
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.729
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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