Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TRIM71Tripartite motif containing 71. (908 aa)    
Predicted Functional Partners:
BICC1
BicC family RNA binding protein 1.
      
 0.868
PUF60
Poly(U) binding splicing factor 60.
      
 0.768
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 0.727
PIM3
Pim-3 proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 
 0.697
SCRIB
Scribble planar cell polarity protein.
    
 0.696
GBE1
1,4-alpha-glucan branching enzyme 1.
      
 0.624
CENPJ
Centromere protein J.
    
 0.613
DPH6
Diphthami_syn_2 domain-containing protein.
    
 
 0.608
LIN28A
Lin-28 homolog A.
   
 
 0.607
CPEB1
Uncharacterized protein.
   
 
 0.600
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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