Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GEN1GEN1 Holliday junction 5' flap endonuclease. (949 aa)    
Predicted Functional Partners:
U3I2H1_ANAPP
Uncharacterized protein.
  
 0.881
DNA2
DNA replication helicase/nuclease 2.
   
 0.816
EME1
Essential meiotic structure-specific endonuclease 1.
   
 0.794
RMI2
RecQ mediated genome instability 2.
   
 
 0.773
SLX4
SLX4 structure-specific endonuclease subunit.
  
 0.773
RMI1
RecQ mediated genome instability 1.
   
 
 0.756
EXO1
Exonuclease 1.
   
 
 0.729
ENSAPLP00000026881
Zinc-hook domain-containing protein.
  
 0.712
SLX1
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
   
 
 0.702
BRCA2
BRCA2 DNA repair associated.
   
 0.691
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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