Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAM189A2Family with sequence similarity 189 member A2. (451 aa)    
Predicted Functional Partners:
SLC35F4
Solute carrier family 35 member F4.
      
 0.850
TJP2
Uncharacterized protein; Belongs to the MAGUK family.
    
 
 0.672
TMEM171
Transmembrane protein 171.
      
 0.664
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2.
      
 0.608
MANSC1
MANSC domain containing 1.
     
 0.606
GNS
N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.
      
 0.548
EBNA1BP2
EBNA1 binding protein 2.
      
 0.548
ENSAPLP00000032118
Uncharacterized protein.
      
 0.547
PACC1
Proton activated chloride channel 1.
      
 0.545
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
      
 0.539
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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