Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (476 aa)    
Predicted Functional Partners:
UBASH3A
Ubiquitin associated and SH3 domain containing A.
   
  
 0.626
SLC26A4
Solute carrier family 26 member 4.
      
 0.547
ENSAPLP00000020537
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.544
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
   
 
 0.512
LOXHD1
Lipoxygenase homology domains 1.
    
 
 0.507
COCH
Cochlin.
     
 0.492
ACE2
Angiotensin-converting enzyme.
    
 
 0.478
TMC3
Transmembrane channel-like protein.
    
 0.477
ENSAPLP00000020316
Uncharacterized protein.
    
 0.477
ILDR1
Immunoglobulin like domain containing receptor 1.
     
 0.468
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (12%) [HD]