Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DONSONDownstream neighbor of SON. (738 aa)    
Predicted Functional Partners:
MCM2
DNA helicase; Belongs to the MCM family.
   
 
 0.920
GINS4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.904
MCM3
DNA helicase; Belongs to the MCM family.
   
 
 0.891
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 
 0.891
CDC45
Cell division cycle 45.
   
 
 0.885
MCM6
DNA helicase; Belongs to the MCM family.
   
 
 0.882
MCM4
DNA helicase; Belongs to the MCM family.
   
 
 0.868
MCM5
DNA helicase; Belongs to the MCM family.
   
 
 0.846
POLD2
DNA polymerase delta 2, accessory subunit.
   
 
 0.798
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.789
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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