STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TREM2Triggering receptor expressed on myeloid cells 2. (209 aa)    
Predicted Functional Partners:
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.751
U3IMM7_ANAPP
Uncharacterized protein.
   
 
0.645
GPNMB
Glycoprotein nmb.
   
  
 0.644
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.634
PTX3
Pentraxin 3.
      
 0.632
TMEM119
Transmembrane protein 119.
      
 0.625
SYK
Spleen associated tyrosine kinase.
   
 
 0.618
U3J0B3_ANAPP
Protein kinase domain-containing protein.
   
 
 0.609
MERTK
Uncharacterized protein.
   
 
 0.609
PICALM
Phosphatidylinositol binding clathrin assembly protein.
      
 0.586
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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