Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
TXNIP
Thioredoxin interacting protein.
    
 0.999
PRDX1
Peroxiredoxin 1.
  
 0.980
MSRA
PMSR domain-containing protein.
  
 0.973
TXN2
Thioredoxin 2.
   
 0.971
PRDX3
Peroxiredoxin 3.
  
 0.939
TXNRD1
Thioredoxin reductase 1.
   
 0.924
MAP3K6
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.923
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.923
PRDX4
Peroxiredoxin 4.
  
 0.921
TXNRD3
Thioredoxin reductase 3.
   
 0.883
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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