Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (383 aa)    
Predicted Functional Partners:
CHTOP
Chromatin target of PRMT1.
   
 
 0.914
ENSAPLP00000023040
Uncharacterized protein.
   
 0.904
ENSAPLP00000028245
Uncharacterized protein.
    
 0.901
CBFB
Core-binding factor subunit beta.
     
  0.901
EP300
E1A binding protein p300.
    
 0.880
RPS2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
 0.850
HDAC8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.813
SERBP1
SERPINE1 mRNA binding protein 1.
   
 
 0.795
CREBBP
CREB binding protein.
    
 0.732
BTG2
BTG anti-proliferation factor 2.
    
 
 0.731
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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