Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
APBA1Amyloid beta precursor protein binding family A member 1. (823 aa)    
Predicted Functional Partners:
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.996
APP
Amyloid beta precursor protein.
   
 
 0.946
ENSAPLP00000017041
Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.880
STXBP1
Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.880
U3HZZ3_ANAPP
PDZ domain-containing protein.
   
 0.847
LIN7A
L27 domain-containing protein.
   
 0.847
LIN7C
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
   
 0.847
MPP1
Membrane palmitoylated protein 1; Belongs to the MAGUK family.
   
 0.845
SLC18B1
Solute carrier family 18 member B1.
     
 0.823
MPP6
Membrane palmitoylated protein 6; Belongs to the MAGUK family.
   
 0.700
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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