Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CHKACholine kinase alpha. (447 aa)    
Predicted Functional Partners:
PCYT2
Phosphate cytidylyltransferase 2, ethanolamine.
   
 
 0.984
U3I6B7_ANAPP
CTP_transf_like domain-containing protein.
   
 
 0.970
U3IS01_ANAPP
CTP_transf_like domain-containing protein.
   
 
 0.964
GPCPD1
Glycerophosphocholine phosphodiesterase 1.
    
 0.921
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
     
 0.911
ETNPPL
Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.910
CHAT
Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.907
ENSAPLP00000020360
Uncharacterized protein.
     
 
0.900
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.735
LMF2
Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.
      
 0.708
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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