WIPI1 protein (Anas platyrhynchos) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

WIPI1

WD repeat domain, phosphoinositide interacting 1. (430 aa)

Predicted Functional Partners:

ATG16L1

0.958

ATG5

0.912

ATG12

0.906

ATG7

0.868

BECN1

0.865

ATG2B

0.839

PIK3C3

0.826

ULK2

0.804

ULK1

0.784

PIK3R4

0.767

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG16L1	ENSAPLP00000030549	ENSAPLP00000013185	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD_REPEATS_REGION domain-containing protein.	0.999
ATG12	ATG2B	ENSAPLP00000030549	ENSAPLP00000025558	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 2B.	0.590
ATG12	ATG5	ENSAPLP00000030549	ENSAPLP00000018253	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSAPLP00000030549	ENSAPLP00000019209	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.999
ATG12	BECN1	ENSAPLP00000030549	ENSAPLP00000004076	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.985
ATG12	PIK3C3	ENSAPLP00000030549	ENSAPLP00000012571	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.938
ATG12	PIK3R4	ENSAPLP00000030549	ENSAPLP00000010174	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphoinositide-3-kinase regulatory subunit 4.	0.904
ATG12	ULK1	ENSAPLP00000030549	ENSAPLP00000014667	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Unc-51 like autophagy activating kinase 1.	0.903
ATG12	ULK2	ENSAPLP00000030549	ENSAPLP00000002861	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Unc-51 like autophagy activating kinase 2.	0.935
ATG12	WIPI1	ENSAPLP00000030549	ENSAPLP00000008697	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	WD repeat domain, phosphoinositide interacting 1.	0.906
ATG16L1	ATG12	ENSAPLP00000013185	ENSAPLP00000030549	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG16L1	ATG2B	ENSAPLP00000013185	ENSAPLP00000025558	WD_REPEATS_REGION domain-containing protein.	Autophagy related 2B.	0.590
ATG16L1	ATG5	ENSAPLP00000013185	ENSAPLP00000018253	WD_REPEATS_REGION domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	ATG7	ENSAPLP00000013185	ENSAPLP00000019209	WD_REPEATS_REGION domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.941
ATG16L1	BECN1	ENSAPLP00000013185	ENSAPLP00000004076	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.930
ATG16L1	PIK3C3	ENSAPLP00000013185	ENSAPLP00000012571	WD_REPEATS_REGION domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.880
ATG16L1	PIK3R4	ENSAPLP00000013185	ENSAPLP00000010174	WD_REPEATS_REGION domain-containing protein.	Phosphoinositide-3-kinase regulatory subunit 4.	0.829
ATG16L1	ULK1	ENSAPLP00000013185	ENSAPLP00000014667	WD_REPEATS_REGION domain-containing protein.	Unc-51 like autophagy activating kinase 1.	0.762
ATG16L1	ULK2	ENSAPLP00000013185	ENSAPLP00000002861	WD_REPEATS_REGION domain-containing protein.	Unc-51 like autophagy activating kinase 2.	0.814
ATG16L1	WIPI1	ENSAPLP00000013185	ENSAPLP00000008697	WD_REPEATS_REGION domain-containing protein.	WD repeat domain, phosphoinositide interacting 1.	0.958