STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIG3DNA ligase. (980 aa)    
Predicted Functional Partners:
ENSAPLP00000028415
XRCC1_N domain-containing protein.
   
 0.999
TDP1
Tyrosyl-DNA phosphodiesterase 1.
   
 
 0.980
APLF
Aprataxin and PNKP like factor.
    
 
 0.978
XRCC6
X-ray repair cross complementing 6.
   
 0.976
RNF146
Ring finger protein 146.
    
 
 0.944
REC114
REC114 meiotic recombination protein.
   
 0.933
U3IFZ0_ANAPP
DNA_pol_B_thumb domain-containing protein.
  
 0.929
ENSAPLP00000024926
HHH_8 domain-containing protein.
  
 0.929
ENSAPLP00000026294
HHH_8 domain-containing protein.
  
 0.929
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
   
 0.874
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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