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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT15Keratin 15; Belongs to the intermediate filament family. (423 aa)    
Predicted Functional Partners:
CDH1
Uncharacterized protein.
    
 0.617
KRAS
KRAS proto-oncogene, GTPase.
    
 0.590
SOX9
SRY-box transcription factor 9.
    
 0.561
CPA1
Carboxypeptidase A1.
     
 0.551
HNF4A
Hepatocyte nuclear factor 4 alpha.
     
 0.544
ENSAPLP00000032898
IF rod domain-containing protein; Belongs to the intermediate filament family.
 
0.495
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.492
COL3A1
Uncharacterized protein.
    
 0.483
COL1A1
Collagen type I alpha 1 chain.
    
 0.483
AFP
Uncharacterized protein.
   
 0.467
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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