PPARG protein (Anas platyrhynchos) - STRING interaction network

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PPARG

Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (450 aa)

Predicted Functional Partners:

PPARGC1A

0.991

RXRA

0.987

EP300

0.978

RXRG

0.977

CREBBP

0.975

CEBPB

0.945

SIRT1

0.939

HDAC3

0.938

CTNNB1

0.921

PPARD

0.920

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPB	CREBBP	ENSAPLP00000021900	ENSAPLP00000020073	CCAAT/enhancer-binding protein.	CREB binding protein.	0.737
CEBPB	EP300	ENSAPLP00000021900	ENSAPLP00000010252	CCAAT/enhancer-binding protein.	E1A binding protein p300.	0.879
CEBPB	HDAC3	ENSAPLP00000021900	ENSAPLP00000027919	CCAAT/enhancer-binding protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.449
CEBPB	PPARG	ENSAPLP00000021900	ENSAPLP00000008758	CCAAT/enhancer-binding protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.945
CEBPB	RXRA	ENSAPLP00000021900	ENSAPLP00000012995	CCAAT/enhancer-binding protein.	Retinoid X receptor alpha.	0.440
CREBBP	CEBPB	ENSAPLP00000020073	ENSAPLP00000021900	CREB binding protein.	CCAAT/enhancer-binding protein.	0.737
CREBBP	CTNNB1	ENSAPLP00000020073	ENSAPLP00000013346	CREB binding protein.	Catenin beta 1.	0.986
CREBBP	EP300	ENSAPLP00000020073	ENSAPLP00000010252	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	HDAC3	ENSAPLP00000020073	ENSAPLP00000027919	CREB binding protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.889
CREBBP	PPARD	ENSAPLP00000020073	ENSAPLP00000004282	CREB binding protein.	Peroxisome proliferator activated receptor delta.	0.419
CREBBP	PPARG	ENSAPLP00000020073	ENSAPLP00000008758	CREB binding protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.975
CREBBP	PPARGC1A	ENSAPLP00000020073	ENSAPLP00000031219	CREB binding protein.	PPARG coactivator 1 alpha.	0.737
CREBBP	RXRA	ENSAPLP00000020073	ENSAPLP00000012995	CREB binding protein.	Retinoid X receptor alpha.	0.629
CREBBP	RXRG	ENSAPLP00000020073	ENSAPLP00000029653	CREB binding protein.	NR LBD domain-containing protein.	0.629
CREBBP	SIRT1	ENSAPLP00000020073	ENSAPLP00000030709	CREB binding protein.	Sirtuin 1.	0.809
CTNNB1	CREBBP	ENSAPLP00000013346	ENSAPLP00000020073	Catenin beta 1.	CREB binding protein.	0.986
CTNNB1	EP300	ENSAPLP00000013346	ENSAPLP00000010252	Catenin beta 1.	E1A binding protein p300.	0.980
CTNNB1	HDAC3	ENSAPLP00000013346	ENSAPLP00000027919	Catenin beta 1.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.674
CTNNB1	PPARG	ENSAPLP00000013346	ENSAPLP00000008758	Catenin beta 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.921
CTNNB1	RXRA	ENSAPLP00000013346	ENSAPLP00000012995	Catenin beta 1.	Retinoid X receptor alpha.	0.467

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