Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
MCUMitochondrial calcium uniporter. (354 aa)    
Predicted Functional Partners:
MICU1
Mitochondrial calcium uptake 1.
    
 0.994
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
    
 0.975
MICU2
Mitochondrial calcium uptake 2.
    
 0.974
MICU3
Mitochondrial calcium uptake family member 3.
    
 0.935
PACS2
Phosphofurin acidic cluster sorting protein 2.
      
 0.719
VDAC1
Voltage dependent anion channel 1.
      
 0.710
MFN2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.684
SPG7
SPG7 matrix AAA peptidase subunit, paraplegin.
     
 0.663
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
   0.656
PHB2
Prohibitin.
     
 0.654
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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