STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
MAP4K3Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (898 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
   
0.925
TNIK
CNH domain-containing protein.
 
    
 0.615
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.568
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.544
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.538
GRB2
Growth factor receptor bound protein 2.
   
 
 0.538
RRAGB
Ras related GTP binding B.
    
 
 0.485
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
   
 
 0.420
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.