Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAPTM5Lysosomal protein transmembrane 5. (258 aa)    
Predicted Functional Partners:
C1QC
Complement C1q C chain.
   
  
 0.969
U3I185_ANAPP
Tetraspanin.
   
  
 0.784
LY86
Lymphocyte antigen 86.
   
  
 0.714
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.637
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.637
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.630
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
  
 0.617
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
   
    0.561
SDC3
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
      
 0.560
PSMD6
Proteasome 26S subunit, non-ATPase 6.
      
 0.545
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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