STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCC8ATP binding cassette subfamily C member 8. (1594 aa)    
Predicted Functional Partners:
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
 
 
 0.998
KCNJ8
Potassium voltage-gated channel subfamily J member 8.
 
 
 0.932
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.801
EIF2AK3
Eukaryotic translation initiation factor 2 alpha kinase 3.
   
  
 0.633
RAPGEF3
Rap guanine nucleotide exchange factor 3.
    
 0.629
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
 
 
 0.626
SERGEF
Secretion regulating guanine nucleotide exchange factor.
    
 
 0.625
PIK3C2A
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
   
  
 0.617
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
  
 
 0.603
NUCB2
Nucleobindin 2.
      
 0.586
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.