Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCC8ATP binding cassette subfamily C member 8. (1594 aa)    
Predicted Functional Partners:
KCNJ11
Potassium voltage-gated channel subfamily J member 11.
   
 0.999
KCNJ8
Potassium voltage-gated channel subfamily J member 8.
   
 0.986
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.965
RAPGEF3
Rap guanine nucleotide exchange factor 3.
    
 0.943
SLC30A8
Solute carrier family 30 member 8.
      
 0.846
ABCC9
ATP binding cassette subfamily C member 9.
  
0.814
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.719
KCNJ2
Potassium voltage-gated channel subfamily J member 2.
    
 0.658
HNF1A
Homeobox domain-containing protein.
   
  
 0.607
USH1C
USH1 protein network component harmonin.
 
  
 0.579
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]