UPF1 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

UPF1

UPF1 RNA helicase and ATPase. (1117 aa)

Predicted Functional Partners:

SMG1

0.999

SMG7

0.999

UPF2

0.999

SMG5

0.998

UPF3A

0.997

EIF4A3

0.995

ENSAPLP00000029661

0.993

RBM8A

0.991

RNPS1

0.988

STAU1

0.979

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4A3	ENSAPLP00000029661	ENSAPLP00000014603	ENSAPLP00000029661	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	Uncharacterized protein.	0.999
EIF4A3	RBM8A	ENSAPLP00000014603	ENSAPLP00000001249	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.995
EIF4A3	RNPS1	ENSAPLP00000014603	ENSAPLP00000026429	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	RNA binding protein with serine rich domain 1.	0.995
EIF4A3	SMG1	ENSAPLP00000014603	ENSAPLP00000011605	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.975
EIF4A3	SMG5	ENSAPLP00000014603	ENSAPLP00000010035	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	SMG5 nonsense mediated mRNA decay factor.	0.821
EIF4A3	SMG7	ENSAPLP00000014603	ENSAPLP00000015728	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	SMG7 nonsense mediated mRNA decay factor.	0.686
EIF4A3	UPF1	ENSAPLP00000014603	ENSAPLP00000008896	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	UPF1 RNA helicase and ATPase.	0.995
EIF4A3	UPF2	ENSAPLP00000014603	ENSAPLP00000029974	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	UPF2 regulator of nonsense mediated mRNA decay.	0.980
EIF4A3	UPF3A	ENSAPLP00000014603	ENSAPLP00000025196	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	UPF3A regulator of nonsense mediated mRNA decay.	0.981
ENSAPLP00000029661	EIF4A3	ENSAPLP00000029661	ENSAPLP00000014603	Uncharacterized protein.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.999
ENSAPLP00000029661	RBM8A	ENSAPLP00000029661	ENSAPLP00000001249	Uncharacterized protein.	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	0.994
ENSAPLP00000029661	RNPS1	ENSAPLP00000029661	ENSAPLP00000026429	Uncharacterized protein.	RNA binding protein with serine rich domain 1.	0.836
ENSAPLP00000029661	SMG1	ENSAPLP00000029661	ENSAPLP00000011605	Uncharacterized protein.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.544
ENSAPLP00000029661	SMG5	ENSAPLP00000029661	ENSAPLP00000010035	Uncharacterized protein.	SMG5 nonsense mediated mRNA decay factor.	0.822
ENSAPLP00000029661	SMG7	ENSAPLP00000029661	ENSAPLP00000015728	Uncharacterized protein.	SMG7 nonsense mediated mRNA decay factor.	0.630
ENSAPLP00000029661	STAU1	ENSAPLP00000029661	ENSAPLP00000010350	Uncharacterized protein.	Staufen double-stranded RNA binding protein 1.	0.403
ENSAPLP00000029661	UPF1	ENSAPLP00000029661	ENSAPLP00000008896	Uncharacterized protein.	UPF1 RNA helicase and ATPase.	0.993
ENSAPLP00000029661	UPF2	ENSAPLP00000029661	ENSAPLP00000029974	Uncharacterized protein.	UPF2 regulator of nonsense mediated mRNA decay.	0.992
ENSAPLP00000029661	UPF3A	ENSAPLP00000029661	ENSAPLP00000025196	Uncharacterized protein.	UPF3A regulator of nonsense mediated mRNA decay.	0.975
RBM8A	EIF4A3	ENSAPLP00000001249	ENSAPLP00000014603	RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.995