STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WWOXWW domain containing oxidoreductase. (402 aa)    
Predicted Functional Partners:
TFAP2C
Transcription factor AP-2 gamma.
    
 0.957
FAM189B
Family with sequence similarity 189 member B.
    
 
 0.834
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
 
 0.796
EGFR
Receptor protein-tyrosine kinase.
    
 0.790
ENSAPLP00000017981
Receptor protein-tyrosine kinase.
    
 0.790
ERBB4
Receptor protein-tyrosine kinase.
    
 0.790
ENSAPLP00000025539
Uncharacterized protein.
    
 
 0.657
WBP2
WW domain binding protein 2.
    
 
 0.656
ENSAPLP00000019451
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
 0.655
VOPP1
VOPP1 WW domain binding protein.
    
 
 0.642
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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