STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF6Interferon regulatory factor 6. (467 aa)    
Predicted Functional Partners:
GRHL3
Grainyhead like transcription factor 3.
    
 
 0.677
CREBBP
CREB binding protein.
    
 0.626
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.534
TBX22
T-box transcription factor 22.
     
 0.527
IL10
Interleukin 10.
    
 
 0.526
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.517
MAVS
CARD_2 domain-containing protein.
    
 0.515
ARHGAP29
Rho GTPase activating protein 29.
   
  
 0.513
IRF1
Interferon regulatory factor 1.
   
 0.485
TLR4
Toll like receptor 4.
   
 0.484
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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