U3IP70_ANAPP protein (Anas platyrhynchos) - STRING interaction network

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Score

U3IP70_ANAPP

Uncharacterized protein. (416 aa)

Predicted Functional Partners:

CYP11A1

0.973

CYP17A1

0.972

CYP7B1

0.968

CYP19A1

0.962

U3IER8_ANAPP

0.957

SRD5A3

0.955

CYP7A1

0.955

U3IRP6_ANAPP

0.953

HSD17B3

0.951

SRD5A1

0.936

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	CYP17A1	ENSAPLP00000016511	ENSAPLP00000012089	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	0.972
CYP11A1	CYP19A1	ENSAPLP00000016511	ENSAPLP00000007334	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	0.705
CYP11A1	CYP7B1	ENSAPLP00000016511	ENSAPLP00000011339	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	0.960
CYP11A1	HSD17B3	ENSAPLP00000016511	ENSAPLP00000005812	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.791
CYP11A1	SRD5A1	ENSAPLP00000016511	ENSAPLP00000011225	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.428
CYP11A1	SRD5A3	ENSAPLP00000016511	ENSAPLP00000006768	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid 5 alpha-reductase 3.	0.545
CYP11A1	U3IER8_ANAPP	ENSAPLP00000016511	ENSAPLP00000005740	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.940
CYP11A1	U3IP70_ANAPP	ENSAPLP00000016511	ENSAPLP00000009043	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein.	0.973
CYP11A1	U3IRP6_ANAPP	ENSAPLP00000016511	ENSAPLP00000009919	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.913
CYP17A1	CYP11A1	ENSAPLP00000012089	ENSAPLP00000016511	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.972
CYP17A1	CYP19A1	ENSAPLP00000012089	ENSAPLP00000007334	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	0.957
CYP17A1	CYP7A1	ENSAPLP00000012089	ENSAPLP00000007735	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.926
CYP17A1	CYP7B1	ENSAPLP00000012089	ENSAPLP00000011339	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	0.919
CYP17A1	HSD17B3	ENSAPLP00000012089	ENSAPLP00000005812	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.973
CYP17A1	SRD5A1	ENSAPLP00000012089	ENSAPLP00000011225	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.	0.951
CYP17A1	SRD5A3	ENSAPLP00000012089	ENSAPLP00000006768	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Steroid 5 alpha-reductase 3.	0.906
CYP17A1	U3IER8_ANAPP	ENSAPLP00000012089	ENSAPLP00000005740	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.905
CYP17A1	U3IP70_ANAPP	ENSAPLP00000012089	ENSAPLP00000009043	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.972
CYP17A1	U3IRP6_ANAPP	ENSAPLP00000012089	ENSAPLP00000009919	Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.915
CYP19A1	CYP11A1	ENSAPLP00000007334	ENSAPLP00000016511	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.705