Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPFIBP1Uncharacterized protein. (907 aa)    
Predicted Functional Partners:
ENSAPLP00000025176
Uncharacterized protein.
 
     0.925
TM7SF3
Transmembrane 7 superfamily member 3.
      
 0.517
CRK
CRK proto-oncogene, adaptor protein.
    
   0.489
PTPRD
Protein tyrosine phosphatase receptor type D.
     
 0.468
PTPRF
Protein tyrosine phosphatase receptor type F.
     
 0.468
PTPRS
Protein tyrosine phosphatase receptor type S.
     
 0.468
PPFIA1
PTPRF interacting protein alpha 1.
   
 0.445
PPFIA4
PTPRF interacting protein alpha 4.
   
 0.445
PPFIA2
PTPRF interacting protein alpha 2.
   
 0.445
YWHAZ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.
    
   0.442
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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