STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCCDCC netrin 1 receptor. (1437 aa)    
Predicted Functional Partners:
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
  0.910
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
  0.910
NTN1
Netrin 1.
    
 0.892
NTN3
Netrin 3.
    
 0.809
U3J2M7_ANAPP
Uncharacterized protein.
   
 0.765
NTN4
Netrin 4.
   
 0.765
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family.
    
 
 0.748
HJV
Hemojuvelin BMP co-receptor.
   
 0.691
NTNG1
Netrin G1.
    
 0.660
UNC5C
Unc-5 netrin receptor C.
    
 0.624
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.