Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)    
Predicted Functional Partners:
REV1
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.996
REV3L
Uncharacterized protein.
    
 0.988
ENSAPLP00000026666
DNA_pol_B domain-containing protein.
    
 0.988
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.981
MAD2L1
Mitotic arrest deficient 2 like 1.
    
 0.977
CHAMP1
Chromosome alignment maintaining phosphoprotein 1.
    
 
 0.953
POLD2
DNA polymerase delta 2, accessory subunit.
    
 0.949
POLD3
Uncharacterized protein.
    
 0.948
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
     
 0.926
POLH
DNA polymerase eta.
   
 0.921
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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