Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
U3IPW5_ANAPPUncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)    
Predicted Functional Partners:
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
 
 
 
 0.929
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
 
  
 
 0.880
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 0.628
ALOX5
Arachidonate 5-lipoxygenase.
   
 
 0.577
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.574
AASDH
Aminoadipate-semialdehyde dehydrogenase.
  
 0.562
NOS2
Nitric oxide synthase; Produces nitric oxide (NO).
 
  
 
 0.561
NIPAL4
NIPA like domain containing 4.
      
 0.544
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.538
CYP11A1
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 
 0.538
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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