STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (752 aa)    
Predicted Functional Partners:
ENSAPLP00000019535
Uncharacterized protein.
 
      0.899
U3I2I6_ANAPP
Protein kinase domain-containing protein.
 
 
  0.888
ANGPT1
Angiopoietin 1.
   
 0.838
ANGPT2
Angiopoietin 2.
   
 0.831
ANGPT4
Angiopoietin 4.
   
 0.715
U3IJT1_ANAPP
Protein kinase domain-containing protein.
 
 
  
 0.703
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
 
 0.693
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
    
 0.642
EMCN
Endomucin.
   
  
 0.636
ENTPD1
Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.
   
  
 0.631
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.