Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DENND6BDENN domain containing 6B. (574 aa)    
Predicted Functional Partners:
SDK1
Sidekick cell adhesion molecule 1.
      
 0.666
RUSC2
RUN and SH3 domain containing 2.
      
 0.665
KIAA0391
PRORP domain-containing protein.
      
 0.604
ATP6V1F
ATPase H+ transporting V1 subunit F.
      
 0.581
UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats.
      
 0.547
ENSAPLP00000022243
Uncharacterized protein.
      
 0.545
PSAT1
Phosphoserine aminotransferase.
      
 0.484
DENND1A
DENN domain containing 1A.
      
 0.463
DENND1B
DENN domain containing 1B.
      
 0.446
TRAPPC6B
Trafficking protein particle complex 6B.
      
 0.444
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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