Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS4COP9 signalosome subunit 4. (371 aa)    
Predicted Functional Partners:
COPS3
COP9 signalosome subunit 3.
   
 0.999
COPS2
COP9 signalosome subunit 2.
   
 0.999
GPS1
G protein pathway suppressor 1.
   
 0.999
COPS5
COP9 signalosome subunit 5.
   
 0.999
COPS8
COP9 signalosome subunit 8.
   
 0.999
COPS7B
COP9 signalosome subunit 7B.
   
 0.997
COPS7A
COP9 signalosome subunit 7A.
   
 0.996
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.985
DDB2
Damage specific DNA binding protein 2.
    
 0.978
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.971
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (10%) [HD]