HDAC9 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

HDAC9

Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1093 aa)

Predicted Functional Partners:

ARID4B

0.741

ARID4A

0.741

MEF2D

0.695

VCP

0.693

SIRT1

0.678

UBE2I

0.671

ENSAPLP00000016618

0.667

WDR90

0.667

ENSAPLP00000016785

0.657

ENSAPLP00000018304

0.657

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ARID4B	ENSAPLP00000005893	ENSAPLP00000003999	AT-rich interaction domain 4A.	AT-rich interaction domain 4B.	0.979
ARID4A	HDAC9	ENSAPLP00000005893	ENSAPLP00000009519	AT-rich interaction domain 4A.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.741
ARID4B	ARID4A	ENSAPLP00000003999	ENSAPLP00000005893	AT-rich interaction domain 4B.	AT-rich interaction domain 4A.	0.979
ARID4B	HDAC9	ENSAPLP00000003999	ENSAPLP00000009519	AT-rich interaction domain 4B.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.741
ENSAPLP00000016618	ENSAPLP00000016785	ENSAPLP00000016618	ENSAPLP00000016785	WD_REPEATS_REGION domain-containing protein.	Thioredoxin domain-containing protein.	0.841
ENSAPLP00000016618	ENSAPLP00000018304	ENSAPLP00000016618	ENSAPLP00000018304	WD_REPEATS_REGION domain-containing protein.	NDK domain-containing protein.	0.841
ENSAPLP00000016618	HDAC9	ENSAPLP00000016618	ENSAPLP00000009519	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.667
ENSAPLP00000016618	WDR90	ENSAPLP00000016618	ENSAPLP00000026438	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.953
ENSAPLP00000016785	ENSAPLP00000016618	ENSAPLP00000016785	ENSAPLP00000016618	Thioredoxin domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.841
ENSAPLP00000016785	ENSAPLP00000018304	ENSAPLP00000016785	ENSAPLP00000018304	Thioredoxin domain-containing protein.	NDK domain-containing protein.	0.687
ENSAPLP00000016785	HDAC9	ENSAPLP00000016785	ENSAPLP00000009519	Thioredoxin domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.657
ENSAPLP00000016785	VCP	ENSAPLP00000016785	ENSAPLP00000004138	Thioredoxin domain-containing protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.487
ENSAPLP00000016785	WDR90	ENSAPLP00000016785	ENSAPLP00000026438	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.841
ENSAPLP00000018304	ENSAPLP00000016618	ENSAPLP00000018304	ENSAPLP00000016618	NDK domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.841
ENSAPLP00000018304	ENSAPLP00000016785	ENSAPLP00000018304	ENSAPLP00000016785	NDK domain-containing protein.	Thioredoxin domain-containing protein.	0.687
ENSAPLP00000018304	HDAC9	ENSAPLP00000018304	ENSAPLP00000009519	NDK domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.657
ENSAPLP00000018304	VCP	ENSAPLP00000018304	ENSAPLP00000004138	NDK domain-containing protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.487
ENSAPLP00000018304	WDR90	ENSAPLP00000018304	ENSAPLP00000026438	NDK domain-containing protein.	Uncharacterized protein.	0.841
HDAC9	ARID4A	ENSAPLP00000009519	ENSAPLP00000005893	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	AT-rich interaction domain 4A.	0.741
HDAC9	ARID4B	ENSAPLP00000009519	ENSAPLP00000003999	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	AT-rich interaction domain 4B.	0.741

page 1 of 2

Server load: low (10%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About