Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
IGFBP2Thyroglobulin type-1 domain-containing protein. (183 aa)    
Predicted Functional Partners:
ENSAPLP00000032361
IGFBP N-terminal domain-containing protein.
 
    
 0.899
IGF2
Insulin like growth factor 2.
   
 0.679
TUBGCP5
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.670
NIPA1
NIPA magnesium transporter 1.
      
 0.669
MIIP
Migration and invasion inhibitory protein.
    
 
 0.591
IGFBP7
Insulin like growth factor binding protein 7.
     
 0.522
IGF1
Insulin like growth factor 1.
     
 0.519
IGFALS
Insulin like growth factor binding protein acid labile subunit.
    
 0.514
CYFIP1
Uncharacterized protein.
      
 0.484
ENSAPLP00000028598
Uncharacterized protein.
      
 0.484
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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