IGFBP2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

IGFBP2

Thyroglobulin type-1 domain-containing protein. (183 aa)

Predicted Functional Partners:

ENSAPLP00000032361

0.907

IGF2

0.652

IGFALS

0.646

NR0B1

0.539

ZBTB20

0.528

PPARGC1A

0.507

TUBGCP5

0.493

NIPA1

0.491

INS

0.481

FZD9

0.466

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000032361	IGF2	ENSAPLP00000032361	ENSAPLP00000020248	IGFBP N-terminal domain-containing protein.	Insulin like growth factor 2.	0.808
ENSAPLP00000032361	IGFALS	ENSAPLP00000032361	ENSAPLP00000004382	IGFBP N-terminal domain-containing protein.	Insulin like growth factor binding protein acid labile subunit.	0.800
ENSAPLP00000032361	IGFBP2	ENSAPLP00000032361	ENSAPLP00000009531	IGFBP N-terminal domain-containing protein.	Thyroglobulin type-1 domain-containing protein.	0.907
FZD9	IGFBP2	ENSAPLP00000007328	ENSAPLP00000009531	Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family.	Thyroglobulin type-1 domain-containing protein.	0.466
FZD9	TUBGCP5	ENSAPLP00000007328	ENSAPLP00000005361	Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family.	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.	0.438
IGF2	ENSAPLP00000032361	ENSAPLP00000020248	ENSAPLP00000032361	Insulin like growth factor 2.	IGFBP N-terminal domain-containing protein.	0.808
IGF2	IGFALS	ENSAPLP00000020248	ENSAPLP00000004382	Insulin like growth factor 2.	Insulin like growth factor binding protein acid labile subunit.	0.432
IGF2	IGFBP2	ENSAPLP00000020248	ENSAPLP00000009531	Insulin like growth factor 2.	Thyroglobulin type-1 domain-containing protein.	0.652
IGF2	INS	ENSAPLP00000020248	ENSAPLP00000012854	Insulin like growth factor 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.532
IGFALS	ENSAPLP00000032361	ENSAPLP00000004382	ENSAPLP00000032361	Insulin like growth factor binding protein acid labile subunit.	IGFBP N-terminal domain-containing protein.	0.800
IGFALS	IGF2	ENSAPLP00000004382	ENSAPLP00000020248	Insulin like growth factor binding protein acid labile subunit.	Insulin like growth factor 2.	0.432
IGFALS	IGFBP2	ENSAPLP00000004382	ENSAPLP00000009531	Insulin like growth factor binding protein acid labile subunit.	Thyroglobulin type-1 domain-containing protein.	0.646
IGFALS	NR0B1	ENSAPLP00000004382	ENSAPLP00000021446	Insulin like growth factor binding protein acid labile subunit.	Nuclear receptor subfamily 0 group B member 1.	0.594
IGFALS	PPARGC1A	ENSAPLP00000004382	ENSAPLP00000031219	Insulin like growth factor binding protein acid labile subunit.	PPARG coactivator 1 alpha.	0.616
IGFALS	ZBTB20	ENSAPLP00000004382	ENSAPLP00000002199	Insulin like growth factor binding protein acid labile subunit.	Zinc finger and BTB domain containing 20.	0.619
IGFBP2	ENSAPLP00000032361	ENSAPLP00000009531	ENSAPLP00000032361	Thyroglobulin type-1 domain-containing protein.	IGFBP N-terminal domain-containing protein.	0.907
IGFBP2	FZD9	ENSAPLP00000009531	ENSAPLP00000007328	Thyroglobulin type-1 domain-containing protein.	Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family.	0.466
IGFBP2	IGF2	ENSAPLP00000009531	ENSAPLP00000020248	Thyroglobulin type-1 domain-containing protein.	Insulin like growth factor 2.	0.652
IGFBP2	IGFALS	ENSAPLP00000009531	ENSAPLP00000004382	Thyroglobulin type-1 domain-containing protein.	Insulin like growth factor binding protein acid labile subunit.	0.646
IGFBP2	INS	ENSAPLP00000009531	ENSAPLP00000012854	Thyroglobulin type-1 domain-containing protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.481