STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPPPTubulin polymerization promoting protein. (276 aa)    
Predicted Functional Partners:
ENSAPLP00000025847
Uncharacterized protein.
      
 0.636
SH3BGRL3
SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family.
      
 0.611
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
 
 0.578
HAPLN2
Hyaluronan and proteoglycan link protein 2.
   
  
 0.574
NIPAL4
NIPA like domain containing 4.
      
 0.558
CAPZA1
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
  
 0.509
DCX
Doublecortin.
      
 0.491
AP3M1
AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.
      
 0.477
KIAA1217
KIAA1217.
      
 0.471
ACTR10
Actin related protein 10; Belongs to the actin family.
      
 0.454
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.