STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (682 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog.
    
 0.998
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.976
SMAD6
Mothers against decapentaplegic homolog.
    
 0.916
SMAD2
Mothers against decapentaplegic homolog.
    
 0.916
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.915
ENSAPLP00000023897
Uncharacterized protein.
    
 0.913
SMAD3
Mothers against decapentaplegic homolog.
    
 0.912
ENSAPLP00000024910
DUF908 domain-containing protein.
 
  
 0.907
ENSAPLP00000025536
Ubiquitin-like domain-containing protein.
    
 0.901
SMAD4
Mothers against decapentaplegic homolog.
   
 0.819
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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