Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ALAS15-aminolevulinate synthase. (634 aa)    
Predicted Functional Partners:
ALAD
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.990
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.932
SARDH
Sarcosine dehydrogenase.
  
 
 0.924
GLDC
Glycine decarboxylase.
  
 
 0.916
DAO
D-amino acid oxidase.
  
 
 0.915
AGXT2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.914
AGXT
Serine--pyruvate aminotransferase.
    
 0.912
PIPOX
Pipecolic acid and sarcosine oxidase.
  
 
 0.912
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
  
 
 0.910
ENSAPLP00000028541
Beta_elim_lyase domain-containing protein.
  
 
 0.910
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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