Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2094 aa)    
Predicted Functional Partners:
CACNA1G
Calcium voltage-gated channel subunit alpha1 G.
  
  
0.922
CACNA1H
Calcium voltage-gated channel subunit alpha1 H.
  
  
0.918
ENSAPLP00000028189
Uncharacterized protein.
 
      0.843
CAV3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 
 0.689
CACNA1D
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
0.680
CACNA1S
Ca_chan_IQ domain-containing protein.
 
 
 0.651
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
     
  0.650
RASGRP1
RAS guanyl releasing protein 1.
     
  0.650
RASGRF2
Ras protein specific guanine nucleotide releasing factor 2.
     
  0.650
RASGRP3
RAS guanyl releasing protein 3.
     
  0.650
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.