Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HK1Hexokinase 1. (925 aa)    
Predicted Functional Partners:
GPI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.976
PFKP
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
 
 0.953
ENSAPLP00000020961
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
 
 0.950
FBP1
Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.
   
 
 0.941
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2.
   
 0.939
PGM1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
   
 
 0.937
MPI
Mannose-6-phosphate isomerase.
    
 0.936
PGM2
Phosphoglucomutase 2.
   
 
 0.931
G6PC2
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.929
G6PC
Glucose-6-phosphatase catalytic subunit.
     
 0.928
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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