STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPBP1DNA topoisomerase II binding protein 1. (1469 aa)    
Predicted Functional Partners:
BRCA1
BRCA1 DNA repair associated.
   
 0.994
BRIP1
Helicase ATP-binding domain-containing protein.
   
 0.993
RAD9A
RAD9 checkpoint clamp component A.
    
 0.989
BARD1
BRCA1 associated RING domain 1.
   
 0.988
CDC45
Cell division cycle 45.
   
 
 0.986
U3I2H1_ANAPP
Uncharacterized protein.
   
 0.978
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.977
MCM5
DNA helicase; Belongs to the MCM family.
   
 
 0.960
ATRIP
ATR interacting protein.
    
 0.953
HUS1
Checkpoint protein; Belongs to the HUS1 family.
    
 0.950
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.