MBD2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MBD2

Methyl-CpG binding domain protein 2. (239 aa)

Predicted Functional Partners:

MTA3

0.919

MTA1

0.919

RBBP4

0.902

RBBP7

0.898

GATAD2A

0.874

HDAC2

0.828

HDAC1

0.828

ENSAPLP00000017587

0.812

CHD4

0.798

CHD5

0.798

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD4	CHD5	ENSAPLP00000014113	ENSAPLP00000018264	Uncharacterized protein.	Chromodomain helicase DNA binding protein 5.	0.545
CHD4	ENSAPLP00000017587	ENSAPLP00000014113	ENSAPLP00000017587	Uncharacterized protein.	Uncharacterized protein.	0.716
CHD4	GATAD2A	ENSAPLP00000014113	ENSAPLP00000017324	Uncharacterized protein.	GATA zinc finger domain containing 2A.	0.863
CHD4	HDAC1	ENSAPLP00000014113	ENSAPLP00000019850	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.834
CHD4	HDAC2	ENSAPLP00000014113	ENSAPLP00000006605	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.818
CHD4	MBD2	ENSAPLP00000014113	ENSAPLP00000009775	Uncharacterized protein.	Methyl-CpG binding domain protein 2.	0.798
CHD4	MTA1	ENSAPLP00000014113	ENSAPLP00000019665	Uncharacterized protein.	Metastasis associated 1.	0.873
CHD4	MTA3	ENSAPLP00000014113	ENSAPLP00000016957	Uncharacterized protein.	Metastasis associated 1 family member 3.	0.873
CHD4	RBBP4	ENSAPLP00000014113	ENSAPLP00000011204	Uncharacterized protein.	RB binding protein 4, chromatin remodeling factor.	0.868
CHD4	RBBP7	ENSAPLP00000014113	ENSAPLP00000011606	Uncharacterized protein.	RB binding protein 7, chromatin remodeling factor.	0.853
CHD5	CHD4	ENSAPLP00000018264	ENSAPLP00000014113	Chromodomain helicase DNA binding protein 5.	Uncharacterized protein.	0.545
CHD5	ENSAPLP00000017587	ENSAPLP00000018264	ENSAPLP00000017587	Chromodomain helicase DNA binding protein 5.	Uncharacterized protein.	0.716
CHD5	GATAD2A	ENSAPLP00000018264	ENSAPLP00000017324	Chromodomain helicase DNA binding protein 5.	GATA zinc finger domain containing 2A.	0.863
CHD5	HDAC1	ENSAPLP00000018264	ENSAPLP00000019850	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.839
CHD5	HDAC2	ENSAPLP00000018264	ENSAPLP00000006605	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.804
CHD5	MBD2	ENSAPLP00000018264	ENSAPLP00000009775	Chromodomain helicase DNA binding protein 5.	Methyl-CpG binding domain protein 2.	0.798
CHD5	MTA1	ENSAPLP00000018264	ENSAPLP00000019665	Chromodomain helicase DNA binding protein 5.	Metastasis associated 1.	0.873
CHD5	MTA3	ENSAPLP00000018264	ENSAPLP00000016957	Chromodomain helicase DNA binding protein 5.	Metastasis associated 1 family member 3.	0.873
CHD5	RBBP4	ENSAPLP00000018264	ENSAPLP00000011204	Chromodomain helicase DNA binding protein 5.	RB binding protein 4, chromatin remodeling factor.	0.881
CHD5	RBBP7	ENSAPLP00000018264	ENSAPLP00000011606	Chromodomain helicase DNA binding protein 5.	RB binding protein 7, chromatin remodeling factor.	0.881