Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MALT1MALT1 paracaspase. (816 aa)    
Predicted Functional Partners:
BCL10
CARD domain-containing protein.
    
 0.999
CARD11
Caspase recruitment domain family member 11.
    
 0.997
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.984
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.980
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.971
CASP8
Caspase 8; Belongs to the peptidase C14A family.
    
 0.956
U3J6D9_ANAPP
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.956
CARD9
Caspase recruitment domain family member 9.
    
 0.938
MAPK13
Mitogen-activated protein kinase 13.
    
  0.907
MAPK12
Mitogen-activated protein kinase.
    
  0.907
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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