Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
U3IRG6_ANAPPGuanylate cyclase. (864 aa)    
Predicted Functional Partners:
NPR2
Guanylate cyclase.
  
  
 
0.904
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.903
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.903
NUDT2
Nudix hydrolase 2.
     
  0.900
NPPC
Natriuretic peptide C.
    
 0.854
MOCS1
Molybdenum cofactor synthesis 1.
   
 
 0.805
GCH1
GTP cyclohydrolase 1.
     
 0.803
PDE5A
Phosphodiesterase.
    
 0.787
ENSAPLP00000023303
PDEase domain-containing protein.
    
 0.772
PDE3A
Phosphodiesterase.
    
 0.772
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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