Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC4Arrestin domain containing 4. (434 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase.
    
 
 0.728
WWP1
E3 ubiquitin-protein ligase.
    
 
 0.716
TXN
Thioredoxin; Belongs to the thioredoxin family.
    
 0.670
ENSAPLP00000031373
C2 domain-containing protein.
    
 
 0.633
ENSAPLP00000032550
Uncharacterized protein.
    
 
 0.633
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.598
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
      
 0.594
CUEDC1
CUE domain containing 1.
    
   0.581
AQP8
Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.
      
 0.577
U3IRD8_ANAPP
Uncharacterized protein.
    
 0.571
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.