Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)    
Predicted Functional Partners:
TPI1
Triosephosphate isomerase.
  
 0.998
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 
 0.998
MPI
Mannose-6-phosphate isomerase.
  
 
 0.995
PGM1
Phosphoglucomutase 1; Belongs to the phosphohexose mutase family.
  
 0.993
TKT
Transketolase.
  
 0.993
PFKP
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
  
 0.990
ENSAPLP00000020961
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
  
 0.990
TALDO1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.989
FBP1
Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.
   
 
 0.986
ADPGK
ADP dependent glucokinase.
    
 0.986
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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