POLL protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

POLL

DNA polymerase lambda; Belongs to the DNA polymerase type-X family. (618 aa)

Predicted Functional Partners:

DCLRE1C

0.897

LIG1

0.821

ENSAPLP00000028415

0.795

FEN1

0.785

LIG4

0.750

WDR11

0.747

XRCC6

0.718

PRKDC

0.708

XRCC5

0.704

U3IBC3_ANAPP

0.695

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCLRE1C	ENSAPLP00000028415	ENSAPLP00000005201	ENSAPLP00000028415	DNA cross-link repair 1C.	XRCC1_N domain-containing protein.	0.448
DCLRE1C	FEN1	ENSAPLP00000005201	ENSAPLP00000001147	DNA cross-link repair 1C.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.408
DCLRE1C	LIG4	ENSAPLP00000005201	ENSAPLP00000001095	DNA cross-link repair 1C.	DNA ligase.	0.960
DCLRE1C	POLL	ENSAPLP00000005201	ENSAPLP00000009939	DNA cross-link repair 1C.	DNA polymerase lambda; Belongs to the DNA polymerase type-X family.	0.897
DCLRE1C	PRKDC	ENSAPLP00000005201	ENSAPLP00000002207	DNA cross-link repair 1C.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.985
DCLRE1C	XRCC5	ENSAPLP00000005201	ENSAPLP00000012611	DNA cross-link repair 1C.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.962
DCLRE1C	XRCC6	ENSAPLP00000005201	ENSAPLP00000004007	DNA cross-link repair 1C.	X-ray repair cross complementing 6.	0.957
ENSAPLP00000028415	DCLRE1C	ENSAPLP00000028415	ENSAPLP00000005201	XRCC1_N domain-containing protein.	DNA cross-link repair 1C.	0.448
ENSAPLP00000028415	FEN1	ENSAPLP00000028415	ENSAPLP00000001147	XRCC1_N domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.826
ENSAPLP00000028415	LIG1	ENSAPLP00000028415	ENSAPLP00000012998	XRCC1_N domain-containing protein.	DNA ligase.	0.918
ENSAPLP00000028415	LIG4	ENSAPLP00000028415	ENSAPLP00000001095	XRCC1_N domain-containing protein.	DNA ligase.	0.917
ENSAPLP00000028415	POLL	ENSAPLP00000028415	ENSAPLP00000009939	XRCC1_N domain-containing protein.	DNA polymerase lambda; Belongs to the DNA polymerase type-X family.	0.795
ENSAPLP00000028415	PRKDC	ENSAPLP00000028415	ENSAPLP00000002207	XRCC1_N domain-containing protein.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.559
ENSAPLP00000028415	U3IBC3_ANAPP	ENSAPLP00000028415	ENSAPLP00000004545	XRCC1_N domain-containing protein.	Uncharacterized protein.	0.578
ENSAPLP00000028415	XRCC5	ENSAPLP00000028415	ENSAPLP00000012611	XRCC1_N domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.589
ENSAPLP00000028415	XRCC6	ENSAPLP00000028415	ENSAPLP00000004007	XRCC1_N domain-containing protein.	X-ray repair cross complementing 6.	0.757
FEN1	DCLRE1C	ENSAPLP00000001147	ENSAPLP00000005201	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA cross-link repair 1C.	0.408
FEN1	ENSAPLP00000028415	ENSAPLP00000001147	ENSAPLP00000028415	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	XRCC1_N domain-containing protein.	0.826
FEN1	LIG1	ENSAPLP00000001147	ENSAPLP00000012998	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.989
FEN1	LIG4	ENSAPLP00000001147	ENSAPLP00000001095	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA ligase.	0.846