STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF366Zinc finger protein 366. (733 aa)    
Predicted Functional Partners:
SH2D1A
SH2 domain containing 1A.
    
 
 0.634
OTX2
Orthodenticle homeobox 2.
    
 
 0.598
TBL1XR1
Transducin beta like 1 X-linked receptor 1.
    
 0.580
U3I3F9_ANAPP
POU domain protein.
    
 0.542
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.523
HHEX
Homeobox domain-containing protein.
   
 
 0.507
PRRX1
Paired related homeobox 1.
    
 
 0.507
TADA3
Transcriptional adaptor 3.
    
 
 0.498
SMYD1
SET and MYND domain containing 1.
   
 0.495
PPWD1
Peptidylprolyl isomerase domain and WD repeat containing 1.
   
 
 0.490
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.